ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 26 Issue : 4 Year : 2018
 
Childhood Idiopathic Thrombocytopenic Purpura (ITP): Over 40 Year Experiences [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 2011; 19(4): 151-160

Childhood Idiopathic Thrombocytopenic Purpura (ITP): Over 40 Year Experiences

Şinasi Özsoylu
Retired Prof of Pediatrics, Hematology and Hepatology, Turkey. Honorer Fellow of American Pediatric Academy and Honorer Member of American Pediatric Soicety.

Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder. Decreased platelet
survival is the main pathogenesis of it, which is related to platelet antibodies (APA). The levels of these antibodies are correlated with relapse and remission which was shown first time by us. Although APA levels decrease in remission but not risappear as studied by us. Among the several approches about ITP treatment, oral megadose methylprednisolone (MDMP) is found to be the cheapest and most effective one. For oral MDMP treatment, admission of the patients is not required and there is some evidences that chronic ITP could be prevented by this approach.

Keywords: child, idiopathic thrombocytopenic purpura, thrombocytopenia


Şinasi Özsoylu. Childhood Idiopathic Thrombocytopenic Purpura (ITP): Over 40 Year Experiences. Med J Islamic World Acad Sci. 2011; 19(4): 151-160

Corresponding Author: Şinasi Özsoylu, Türkiye


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