ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 26 Issue : 4 Year : 2018
 
Cardiovascular Evaluation of Ruellia Patula and Ruellia Brittoniana [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 1992; 5(1): 67-71

Cardiovascular Evaluation of Ruellia Patula and Ruellia Brittoniana

M. Farid Akhtar, Shahid Rashid, Mansoor Ahmad, K. Usmanghani
From Department of Pharmacognosy and Pharmacology, Faculty of Pharmacy, University of Karachi, Karachi-75270, Pakistan.

Cardiovascular profile of Ruellia patula and Ruellia Brittoniana was carried on isolated rabbit heart. Crude extract, butanolic and aqueous layer of both plants were tested on heart rate, force of contraction and coronary flow. Digoxin was used as a controlled drug. All the fractions showed an increase in force of contraction expect n-butanolic fraction of R. brittoniana which exhibited depression in all parameters. Coronary flow and heart rate displayed non significant decrease. Therefore it was concluded that the given Ruellia plants are of cardiotonic nature.

Keywords: Ruellia patula, R. brittoniana, Cardiovascular evaluation


M. Farid Akhtar, Shahid Rashid, Mansoor Ahmad, K. Usmanghani. Cardiovascular Evaluation of Ruellia Patula and Ruellia Brittoniana. Med J Islamic World Acad Sci. 1992; 5(1): 67-71

Corresponding Author: M. Farid Akhtar, Pakistan


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