ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 26 Issue : 4 Year : 2018
 
Pulmonary Artery and Capillary Prostaglandin Like Activity in Cases with Pulmonary Hypertension of Various Etiology [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 1990; 3(4): 318-324

Pulmonary Artery and Capillary Prostaglandin Like Activity in Cases with Pulmonary Hypertension of Various Etiology

Metin Özenci1, Atila Bozkurt2, Hatice Özenci1
1From Division of Cardiology, Faculty of Medicine, Ankara University, Ankara, Türkiye.
2From Department of Pharmacology, Faculty of Medicine, Hacettepe University, Ankara, Türkiye.

The determination of PGLA by bioassay method from the Pa and Pc blood samples of patients -20 with passive pulmonary hypertension due to valvular heart disease, 3 with primary pulmonary hypertension, 1 with chronic constrictive pericarditis and high pulmonary pressure, 1 with pulmonary hypertension due to pulmonary branch stenosis, totally 25, and 13 cases who had pulmonary hypertension due to pulmonary disease (chronic cor pulmonale)- were performed. Twentyone persons who had cardiac catheterization of various reasons were used as control group and the values were compared. In control group PaPGLA values were significantly high (p<0.0001) from PcPGLA, while the group with pulmonary hypertension of mechanical factors had an unversed and significant ratio (p<0.05) and the difference in the group of chronic cor pulmonale was insignificant (p<0.05). In our opinion while the lung is a PG metabolizing organ normally in pulmonary hypertension, if parenchymal disease does not exist, it acts as a PG releasing organ.

Keywords: Prostaglandins, pulmonary hypertension, PGLA


Metin Özenci, Atila Bozkurt, Hatice Özenci. Pulmonary Artery and Capillary Prostaglandin Like Activity in Cases with Pulmonary Hypertension of Various Etiology. Med J Islamic World Acad Sci. 1990; 3(4): 318-324

Corresponding Author: Metin Özenci, Türkiye


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