Estrogen and Progesterone Receptor Contents in Hepatocellular CarcinomaSemra Paydas, Canan Ersöz, Berksoy Sahin, Gülfiliz Gönlüsün, Ertugrul Seyrek, Ayse YılmazFrom Departments of Oncology and Pathology, Çukurova University, Faculty of Medicine, 01330 Balcali, Adana, Türkiye.
Estrogen and progesterone receptor content (ER-PR) were studied by immunohistochemistry in 25 cases with hepatocellular carcinoma (HCC) and 28 cases with chronic liver disease (CLD). 21 of 25 HCC samples were positive for ER and 8 of them had strong staining. 12 of 28 cases with CLD was positive for ER and all of them had weak staining. The result of anti-estrogen-tamoxifen therapy in one case was discussed. This study suggests that ER is found in high incidence in HCC and anti-estrogen therapy must be evaluated in larger study groups. Keywords: Estrogen receptor, progesterone receptor, hepatocellular carcinoma, chronic liver disease.
Semra Paydas, Canan Ersöz, Berksoy Sahin, Gülfiliz Gönlüsün, Ertugrul Seyrek, Ayse Yılmaz. Estrogen and Progesterone Receptor Contents in Hepatocellular Carcinoma. Med J Islamic World Acad Sci. 1992; 5(4): 300-304
Corresponding Author: Semra Paydas, Türkiye |
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