ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 27 Issue : 1 Year : 2019
 
Effects of Prolonged Administration of Delta -9-Tetrahydrocannabinol in Rat Kidney Cells [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 1989; 2(1): 44-47

Effects of Prolonged Administration of Delta -9-Tetrahydrocannabinol in Rat Kidney Cells

Alparslan Özyazıcı
From the Department of Histology - Embriology, Hacettepe University Medical Center, Ankara, Türkiye.

Kidneys of tetrahydrocannabinol (THC) treated rats were studied by electron microscope and compared to those of normal controls. The experimental group received THC for five weeks twice daily while control animals received saline. The most important differences between these two groups were observed in lysosomes. In addition to these minor changes several large secondary lysomes were observed in the cells of proximal convoluted tubules of the delta -9- THC treated rats. The mitochondria of the experimental group were also degenerated in some cells. The morphology of filtration barrier however appeared normal in glomeruli of THC treated rats.

Keywords: Delta -9 Tetrahydrocannabinol, Glomerulus, Proximal Convoluted Tubules, Mitochondria, Lysosomes.


Alparslan Özyazıcı. Effects of Prolonged Administration of Delta -9-Tetrahydrocannabinol in Rat Kidney Cells. Med J Islamic World Acad Sci. 1989; 2(1): 44-47

Corresponding Author: Alparslan Özyazıcı, Türkiye


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