ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 26 Issue : 4 Year : 2018
 
Ergosterol Production Under Optimized Conditions by Penicillium Crustosum Thom [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 1990; 3(1): 30-34

Ergosterol Production Under Optimized Conditions by Penicillium Crustosum Thom

Khaled M. Ghanem, Nevine B. Ghanem, Abdelmonem H. El-Refai
From Botany Department, Faculty of Science, Alex., Univ. Alexandria and Microbiological Chemistry Laboratory, NRC, Cairo, Egypt.

Penicillium crustosum Thom was succesfully used for sterols production using clarified beet molasses (BM) as the sole carbon source. High yields of sterols and ergosterol were accumulated in the presence of some streol precursors (squalene or pyruvate). A cheep and economic fermentation medium that favoured maximum streol and ergostrerol yileds was found to contain the following ingredients (g/1): H2SO4-treated BM, 90; corn steep solid, 30; initial pH 7.0 and incubation period for 8 days. The GLC analyses revealed the formation of ergosterol (62.1%), stigmasterol (17.2%), fungisterol (16.4%), and lanosterol (4.3%).

Keywords: Penicillium crustosum, ergosterol, beet molasses (BM)


Khaled M. Ghanem, Nevine B. Ghanem, Abdelmonem H. El-Refai. Ergosterol Production Under Optimized Conditions by Penicillium Crustosum Thom. Med J Islamic World Acad Sci. 1990; 3(1): 30-34

Corresponding Author: Khaled M. Ghanem, Egypt


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