ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 25 Issue : 1 Year : 2017
 
Clinical Study of Ziabetus Shakari (Diabetes Mellitus Type 2) and Comparative Evaluation of Unani Formulation (Maghz Tukhm-e-Jamun wa Tukhm-e-Hayat) and Metformin in its Management [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. Ahead of Print: IAS-37888 | DOI: 10.5505/ias.2017.37888  

Clinical Study of Ziabetus Shakari (Diabetes Mellitus Type 2) and Comparative Evaluation of Unani Formulation (Maghz Tukhm-e-Jamun wa Tukhm-e-Hayat) and Metformin in its Management

Mohd. Yunus Siddiqui, Md. Wasi Akhtar, Jamal Azmat, Abdul Khalique
Department of Moalejat, Faculty of Unani Medicine, Aligarh Muslim University, Aligarh, India

Type 2 Diabetes Mellitus is a major health concern of 21st century which is largely preventable but remains responsible for millions of deaths annually and many life-threatening complications. The present study was conducted to evaluate the efficacy of Withania coagulans Dunal and Eugenia jambolana Lam with standard control Metformin in the management of Type 2 Diabetes Mellitus.
It was a randomized open study with standard control. 60 diagnosed cases of type 2 diabetes mellitus were randomly allocated in test (n=30) and control group (n=30). Test drug, Eugenia jambolana 6 gram in powder form and oral infusion of Withania coagulans 10 pieces and control drug Metformin 500 mg were administered to the participants twice daily for 90 days. The subjective parameters were assessed at every follow up, blood sugar recorded at monthly interval, while HbA1c, RFT and lipid profile recorded at baseline and at the termination of trial. The study outcome was analyzed by appropriate statistical tests. Test drug showed significant improvement at par to the control drug in subjective (polydipsia, polyphagia, fatigue, weight loss…) and objective (blood sugar, glycated hemoglobin, RFT, S. Cholesterol, and S. Triglyceride) parameters without any side effects or toxicity. The study infers that the drug is safe and effective in management of type 2 diabetes mellitus.

Keywords: Withania coagulans, Eugenia jambolana, Type 2 Diabetes mellitus, Ziabetus Shakari, Tukhm-e-Hayat, Jamun




Corresponding Author: Md. Wasi Akhtar, India


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