ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 26 Issue : 4 Year : 2018
 
Hypoglycemic Effect of Aloe Vera Extract in Alloxan-Induced Diabetic Albino Rats [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 2011; 19(3): 127-130

Hypoglycemic Effect of Aloe Vera Extract in Alloxan-Induced Diabetic Albino Rats

Saghir A. Jafri1, Syed S. Hasan1, Aftab Nadeem2, Saeeda Kalsoom1, Javed Iqbal2
1Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.
2Department of Pathology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.

The present study was aimed to evaluate the antidiabetic activity of leaf extract of Aloe vera on forty adult male albino rats weighing 200-300 mg body weight (BW) which were divided into four groups (A, B, C and D), Group A served as control, Group B included normal rats treated with Aloe vera leaf extract (0.5 ml/100 gm BW), Group C and D were made diabetic by alloxan injection (65 mg/100 gm BW). Group C served as diabetic control while Group D was given Aloe vera leaf (AVL) extract at the same dose to Group B for 30 days. After 30 days the blood serum was analyzed for serum glucose level in all the four Groups. Twenty rats were randomly taken from these 40 rats for a follow up study and were not given AV extract. The serum glucose level was significantly (P 0.05) decreased in AVL extract feeded rats in Group B and D indicating its hypoglycemic effect.

Keywords: aloe vera, diabetic, albino rats, alloxan


Saghir A. Jafri, Syed S. Hasan, Aftab Nadeem, Saeeda Kalsoom, Javed Iqbal. Hypoglycemic Effect of Aloe Vera Extract in Alloxan-Induced Diabetic Albino Rats. Med J Islamic World Acad Sci. 2011; 19(3): 127-130

Corresponding Author: Saghir A. Jafri, Pakistan


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