ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 26 Issue : 4 Year : 2018
 
Phytochemical and Biological Studies of Butea Frondosa Roxb. Leaves Growing in Egypt [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 2011; 19(4): 173-180

Phytochemical and Biological Studies of Butea Frondosa Roxb. Leaves Growing in Egypt

Nagwa M. Ammar1, Mohammed S. Hefnawy2, Doha A. Mohamed3, Nabil E. Khamis4, Ahmed H. Afifi1, Tom J. Mabry5
1Pharmacognosy Department, National Research Centre, Dokki, Cairo,Egypt.
2Pharmacognosy Department, Faculty of Pharmacy, Cairo Univeristy, Egypt.
3Food Sciences and Nutrition Department, National Research Centre, Dokki, Cairo, Egypt.
4Tanning Materials and Protein Chemistry Department, National Research Centre, Dokki, Cairo,Egypt.
5Molecular Cell and DevelopmentalBiology,The Schoolof Biological Science Department, Texas University, USA.

This study aimed to the discovery of new biologically active natural products with hormonelike activity from Butea frondosa Roxb., Family Leguminosae growing in Egypt. The investigation of estrogenlike activity showed that both the successive non-polar and methanolic extracts showed a significant estrogen-like activity in immature female rats. GLC analysis the non-polar bioactive revealed the presence of eicosane (22.5%) and -amyrin (20.5%) as the major components in the unsaponifiable matter, while palmitic (24.9%) and linoleic (36.8%) acids were the main saturated and unsaturated fatty acids. The successive bioactive methanolic extract was subjected to chromatographic separation to yield five flavonoids identified as vicenin II, vitexin, chrysoeriol 7-o--D-glucuronic acid, 6,8-di-C-rhamnosyl apigenin and luteolin.

Keywords: butea frondosa, estrogenic like activity, bioactive compounds


Nagwa M. Ammar, Mohammed S. Hefnawy, Doha A. Mohamed, Nabil E. Khamis, Ahmed H. Afifi, Tom J. Mabry. Phytochemical and Biological Studies of Butea Frondosa Roxb. Leaves Growing in Egypt. Med J Islamic World Acad Sci. 2011; 19(4): 173-180

Corresponding Author: Doha A. Mohamed, Egypt


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