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Volume : 27 Issue : 1 Year : 2019
 
Effect of Hypothermia on Rat Brain ATPase Activity [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 1990; 3(3): 195-197

Effect of Hypothermia on Rat Brain ATPase Activity

G. Abilova
From Problem Neurochemistry Laboratory, Daghestan State University, Makhachkala, USSR.

The study deals with the activity of Na, K-ATPase and Mg-ATPase in rat sub cellular fractions and cerebral cortex homogenates and its response to 20C hypothermia during 1 and 3 hours with the intra-abdominal injection of neuropeptide dalargin. The results show that the prolonged hypothermia for 1 and 3 hours intensifies the activity of Na, K-ATPase in all examined fractions with the only exception Mg-ATPase in mitochondrial fraction where 3 hours hypothermia brings the activity down. Intra-abdominal injection of dalargin (200g/kg) considerably abates the activity of Na, KATPase during 1 hour hypothermia. Under the discussion are the possible causes that advance the activity of Na, K-ATPase with the influence of hypothermia.

Keywords: Hypothermia, Na, K-ATPase, Mg-ATPase.


G. Abilova. Effect of Hypothermia on Rat Brain ATPase Activity. Med J Islamic World Acad Sci. 1990; 3(3): 195-197

Corresponding Author: G. Abilova, Russia


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