Study of Blood Pressure Patterns Versus Serum Lipid Parameters in Obese Human SubjectsMuhammad S. Akhtar1, Syeda M. Ansar2, Naheed Abbas2, Nazir Ahmad11Department of Physiology, Department of Animal Reproduction, University of Agriculture, Faisalabad- 38040, Pakistan. 2Rural Home Economics, University of Agriculture, Faisalabad- 38040, Pakistan.
A study was conducted to determine relationship of obesity with the blood pressure patterns and lipid parameters in preview of its unique local diet patterns. A total of 200 non-diabetic human subjects of either sex were included in the study. They were categorized on the basis of body mass index (BMI) as obese and non-obese. Each group was further divided into 2 subgroups; hypertensive and normotensive. Fasting lipid profile (total cholesterol, LDL-and HDL-Cholesterols and total triglycerides) in each group was determined to compare the levels among various groups. BMI was calculated from height and weight, while blood pressure was measured with a sphygmomanometer. Lipid profile was determined with Merck kits. Diet and related information was also collected from the patients directly. Means of all parameters, except LDL-C, were higher in females than males; among these BMI and HDL-C showed significant difference. There was a significant negative correlation of diastolic blood pressure with HDL-C in obese subjects; all the other parameters were non-significantly correlated. In the non-obese subjects, there was a significant positive correlation between systolic (SBP) and diastolic (DBP) blood pressures and LDL-C. All other parameters were found non-significantly correlated. The analysis of variance was done in four groups namely, obese non-hypertensives, obese hypertensives, non obese non-hypertensives and non obese hypertensives. BMI, SBP, DBP, LDL-C and total cholesterol had significantly different means in the above four groups, while HDL-C and total triglycerides were statistically non-significant (p>0.05) among four groups. Keywords: Blood pressure, Serum lipids, Obesity.
Muhammad S. Akhtar, Syeda M. Ansar, Naheed Abbas, Nazir Ahmad. Study of Blood Pressure Patterns Versus Serum Lipid Parameters in Obese Human Subjects. Med J Islamic World Acad Sci. 2006; 16(1): 5-10
Corresponding Author: Muhammad S. Akhtar, Pakistan |
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