The Liver Hemosiderosis in Beta-Thalassemia Intermedia and Hemoglobin H DiseaseR. Koçak, F. Baslamıslı, N. Tunalı, N. Z. AlparslanFrom Departments of International Medicine, Pathology and Biostatistics, Çukurova University Faculty of Medicine, Adana, Türkiye.
To evaluate the degree of secondary hemochromatosis, liver biopsies were taken from 5 patients with ß-thalassemia intermedia and three patients with hemoglobin H disease. The morphological and the clinical findings were compared. The serum ferritin level was correlated with the grade of hemosiderosis (R=0.818). The age of the patients (R=0.340) and the amount of transfusion (R=0.207) however, were not found related. Patients Splenectomized earlier had developed higher degrees of hemosiderosis. Keywords: Thalassemia, hemoglobin H, ferritin, chelation, hemosiderosis, liver.
R. Koçak, F. Baslamıslı, N. Tunalı, N. Z. Alparslan. The Liver Hemosiderosis in Beta-Thalassemia Intermedia and Hemoglobin H Disease. Med J Islamic World Acad Sci. 1993; 6(1): 42-45
Corresponding Author: R. Koçak, Türkiye |
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