ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 27 Issue : 3 Year : 2019
 
Biochemical Study on The Efficacy of Malaysian Honey on Inflicted Wounds: An Animal Model [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 2000; 13(3): 125-132

Biochemical Study on The Efficacy of Malaysian Honey on Inflicted Wounds: An Animal Model

A. M. Aljady1, M. Y. Kamaruddin1, A. M. Jamal2, M. Y. Mohd. Yassim3
1Department of Biochemistry, Faculty of Medicine, University Malaya, Malaysia.
2Department of Orthopedic Surgery, Faculty of Medicine, University Malaya, Malaysia.
3Department of Medical Microbiology, Faculty of Medicine, University Malaya, Malaysia.

The efficacy of Malaysian honey on the healing of wounds in Sprague-Dawley rats was investigated on the basis of biophysical and biochemical changes. Equidimensiona full-thickness excision wounds were created on the back of each animal and treated either by topical application or by a combination of topical and oral administration of honey. Control animals received only saline. Development of wound healing was evaluated by measuring the rates of wound contraction and epithelialization. Quantitative assays were performed to determine the amounts of uronic acid, hexosamine, DNA, and collagen content of the granulating tissues. The serum albumin level was also measured. The results obtained showed that honey accelerates wound healing by influencing cell division and proliferation, collagen synthesis and maturation, wound contraction and epithelialization. All the parameters measured showed remarkable consistency with the wound healing property of honey. Honey also improved the nutritional state of the animal when given orally.

Keywords: Honey, wound healing, inflicted wounds.


A. M. Aljady, M. Y. Kamaruddin, A. M. Jamal, M. Y. Mohd. Yassim. Biochemical Study on The Efficacy of Malaysian Honey on Inflicted Wounds: An Animal Model. Med J Islamic World Acad Sci. 2000; 13(3): 125-132

Corresponding Author: M. Y. Kamaruddin, Malaysia


TOOLS
Full Text PDF
Print
Download citation
RIS
EndNote
BibTex
Medlars
Procite
Reference Manager
Share with email
Share
Send email to author

Similar articles
PubMed
Google Scholar




   
Copyright 2023 medicaljournal-ias.org. All Rights Reserved.