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A schiff base acetone semicarbazone has been synthesized and characterized. Its anticancer activities have been studied against Ehrlich Ascites Carcinoma (EAC) cells in swiss albino mice by monitoring the parameters like tumour cell growth inhibition, tumour weight, survival time, peritoneal cells and haematological parameters. It was found that this compound significantly reduces tumour cell growth rate, decreases tumour weight and increases life span in comparison to those of EAC bearing mice. The test compound restored the depleted haematological parameters of EAC bearing mice towards normal. The compound also enhanced number of macrophages in normal mice. The results obtained were compared with those obtained with the standard drug bleomycin.

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To analyze factors which effect diabetes health literacy (DHL) situations of patients with type 2 diabetes and their relations with sociodemographic variables.
Data were collected in a policlinic of a public hospital between 1 and 30 December 2010 through questionnaires from patients with type 2 diabetes who were older than 18 years and accepted to be interviewed. For each correct answer related to DHL situations, the variable was given 1 point and for others, 0 point was given. Thus, a scoring was made to evaluate DHL levels.
62,2% of participants were women, 81,4% were over 44, 23,8% were illiterate, 53,3% were unemployed, 32% had a monthly income equal to or below 700 TL. It was found that 38,8% of participants had difficulties in reading and writing skills. 61,1% of participants had type 2 diabetes for five years and longer, 21,5% did not show up regularly for control, 71,7% never attended educational meetings for diabetes, 93,5% did not know their HbA1c values, 16,9% changed potions without asking their doctors, and 33,9% wrongly interpreted usage instruction sample (3×1 drug use). There was a significant difference between participants’ DHL scores and education status (p0,001). DHL averages of patients whose duration of illness was 5 to 14 years were significantly higher than those whose duration of illness was less than 4 years or more than 15 years (p=0,036). Estimated relative risk in regression model of being high in comparison to those having difficulty in at least one of reading or writing activities was 2,697 (95%GA: 1,208-6,022). The estimated relative risk of being high for DHL scores of those, whose duration of illness was 15 and more years, was equal to 5,437 (95%GA: 1,798-16,436) in comparison to patients who had been diseased for 4 or fewer years.
Factors such as education, reading and writing skills, area of settlement, and family support which have all been found to affect DHL scores should be given due attention in treatments of patients with type 2 diabetes.

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Sinusitis is the symptomatic inflammation of the paranasal sinuses, which may be due to infection, allergy or autoimmune causes. It usually occurs due to a viral infection and resolve over the course of 10 days. It is a common disease affecting more than 24 million people annually. Its prevalence is escalating in different geographical locations of the world, especially in cold regions. The best way to prevent sinusitis is to educate the people about risk factors and preventive strategies. The present study was planned with an objective to know the prevalence of sinusitis and to determine the ratio of diseases in respect of Mizaj (Temperament) of the patients attending Govt. Unani Hospital Srinagar and AYUSH Centres in Kashmir. The study was an observational multi-centric cross sectional hospital based survey. A total of 11514 patients of any age group and sex, attending the out-patients departments of these centres, irrespective of the treatment seeking for were screened after obtaining approval from Institutional Ethical Committee. A pre-tested semi-structured questionnaire which was based on the demographic profile and risk factors of sinusitis was administered to collect the relevant data. The results showed that overall prevalence of sinusitis was 1.11%. The mean age of patients was 34 years and 70% of patients were suffering from chronic maxillary sinusitis. The study revealed that 20% of patients have positive family history of sinusitis. The history of allergy and cold exposure was found in 30 % of patients. The prevalence was highest in patients having Balgami (phlegmatic) temperament. It can be concluded that by knowing ones temperament, the risk for developing sinusitis can be predicted and preventive strategies may be adopted at individual and mass levels.

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To evaluate cytokine production in women with unexplained pregnancy loss.
The study enrolled 84 women age 15-41 years with a mean age of 25.07 ± 6.6, during the period from September 2011 till March 2012 from Basrah Hospitals, Iraq. The patients group comprised 46 women with first trimester miscarriage. The control group included 38 women with first trimester successful pregnancy with no history of miscarriage. Cytokines were measured by ELISA.
There were significantly higher levels of IFN-, TNF-, IL-2 and IL-10 in the aborted women as compared to the controls. In relation to IL-4 and IL-6 non-significant difference was detected between women with miscarriage and control groups. Significant effect of age on serum IL-2 and IL-10 in women with first trimester miscarriage was recorded while no effect observed in the levels of IFN-, TNF-, IL-4 and IL-6. Furthermore, significant higher level of all Th-1 cytokines for miscarriage group than control group for women aged 25-34 years was noticed. In contrast, non-significant differences were found between estimated level for miscarriage and control groups of all Th-1 cytokines for age group >34 years.
This study supports the hypothesis of role of Th-1 produced cytokines in the pathogenesis of miscarriage.

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Compact -forming ability of a multi-component paracetamol tablet formulations with varying amounts of modified Maize Starch incorporated as external disintegrant was studied with a view to know the influence of the increase on compaction characteristics and the quality of resulting tablets. Three formulations coded B-1, B-2 and B-3 with similar constituents but varying amount of modified Maize starch were designed and prepared by wet granulation process to yield granules that were compacted into tablets. Data and information were collected from out-of-die method; using hand operated tablet press at 5 predetermined pressures and fitted into Heckel plots. Compaction behaviours and mechanical properties of the tablets were evaluated.
The three formulations showed consolidation by deformation but at different levels. Sample B-3 which has highest concentration of modified Maize starch seemed to perform on the average better than B-2 and B-1. Mean yield pressure vindicated the ease of compression of granules to be B-3 > B-1 > B-2. It is inferred that modified Maize starch could be used to moderate the compaction characteristics of pharmaceutical agglomerates and mechanical properties of resulting tablets. Lower values of yield pressure, constant A, and relative density of B-3 justified the increase in concentration to be beneficial to the formulation. B-3 had highest concentration of modified Maize starch and showed less resistance to consolidation, decrease in granules fragmentation and fast onset of deformation.

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Meckel diverticulitis is the most common congenital abnormality of the gastrointestinal tract. It is presented with intestinal obstruction and bleeding in early ages of life while it is usually diagnosed incidentally in adults. It is formed with the closure of omphalomesenteric duct at 5-7 th gestational week. In this study, we present a case with meckel diverticulitis where it connects to anterior abdominal wall with obstructing intestine causing ileus.

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