Local Ibuprofen Treatment in Gonarthrosis

The purpose of this study was to observe the effects of topical forms of Nonsteroidal antiinflammatory drugs (NSAID) which are widely used in the treatment of rheumatological diseases. NSAIDs are presented to the market in the form of tablets, suppositories, injectable and topical forms. The usage of these tablets, suppositories and injectable forms frequently produce some side effects, especially concerning the gastrointestinal system. The aim of topical application of the same drugs is to decrease these complications. From the results of this study we conclude that topical forms of NSAID can safely and effectively be used to reduce the complications of prolonged application of these pharmaceuticals.