Chemical Medifications of Poly (Methyl Methacrylite) Resins for Binding Reactive Moeities

Chemical functionalizations of the hydroxymethyl groups of the reduced poly (methyl methacrylate), PMMA, resins have been achieved by esterification and etherification reactions to produce halogen containing polymers. However, in an attempt to achieve quantitative conversions of the hydroxymethyl into other reactive functional groups, activation of the reduced PMMA resins by tosylation has been carried out. The tosylated polymer is transformed into polymeric ether, thioether and amino derivatives by substitution reactions of the tosyloxy group with a number of nucleophilic reagents. The tosyloxy groups of this active polymer intermediate are good leaving groups for these displacement reactions as indicated by the degree of substitutions. The activity of the polymeric reagents based on PMMA resins has been examined in the direct bromination reactions of various organic compounds such as carbonyl compounds containing -hydrogen, alkenes and arenes.