The Effects of Cadmium on The Fragility of Red Blood Cell

In order to investigate the effects of cadmium induced lipid peroxidation on red blood cell membrane this experimental study was undertaken. Rats were given drinking water containing 15 ppm CdCI2 for 30 days and the fragility of red blood cells obtained from cadmium exposed rats were compared with those of controls.
Despite the fact that obvious cadmium induced lipid peroxidation as indicated by increased blood TBARS, elevated phospholipids and protein contents of red blood cell membrane here was no significant changes in the fragility of erythrocytes in cadmium treated rats.
This unaltered red blood cell fragility suggested us that red blood cell membrane is more resistant to peroxidative stress than other cells and this resistance seems to be helpful in the maintenance of tissue oxygenation.