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Med J Islamic World Acad Sci. 1993; 6(2): 99-107
Synthesis of Some 6-(Alkylamino) Methyl Hexahydro-5-Aryl-And Aralkyl-4, 7-Methanoindan-5-Ols and Certain of Their Propionate Esters as Analgesics M. Nabil Aboul-Enein, A. A. El-Azzouny, N. A. Abdallah, S. M. Moharam, W. Werner, A. Eid, A. A. Makhluf From Department of Pharmaceutical Sciences, National Research Centre, Dokki, Cairo, Egypt. The synthesis and screening of the analgesic activity of a series of 6-(alkylamino) methyl hexahydro-5-aryl-and aralkyl-4,7-methanoindan-5-ols (2 a-p) and the corresponding propionate esters 6b, c, g, k and m are described. Some of these tertiary alcohols exhibited slight analgesic potency comparable with that of Tramadol i the hot-plate test. Keywords: 6-(Alkylamino) methyl hexahydro-5-aryl-and aralkyl-4, 7-methanoindan-5-ols, propionate esters, analgesics. M. Nabil Aboul-Enein, A. A. El-Azzouny, N. A. Abdallah, S. M. Moharam, W. Werner, A. Eid, A. A. Makhluf. Synthesis of Some 6-(Alkylamino) Methyl Hexahydro-5-Aryl-And Aralkyl-4, 7-Methanoindan-5-Ols and Certain of Their Propionate Esters as Analgesics. Med J Islamic World Acad Sci. 1993; 6(2): 99-107 Corresponding Author: M. Nabil Aboul-Enein, Egypt	TOOLS Full Text PDF Print Download citation RIS EndNote BibTex Medlars Procite Reference Manager Share with email Share Send email to author Similar articles PubMed Google Scholar