ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
 
             
 
Volume : 27 Issue : 3 Year : 2019
 
Synthesis of Some New Heterocyclic Compounds with Expected Potential Biological Activity [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 1989; 2(4): 237-240

Synthesis of Some New Heterocyclic Compounds with Expected Potential Biological Activity

Evelin Boshra Moawad
From Chemistry Department, Faculty of Science, Mansoura University, Mansoura, Egypt.

Condensation of 4-acetylphenyl-3', 4'-xylene sulphonate with ethyl acetate in presence of sodium metal gave the 1,3-diketone (1). Reaction of 1 with hydrazine hydrate, phenyl hydrazine, hydroxylamine, o-aminophenol and thiourea has been studied. Condensation of 3,4-xylene sulphonate ester of p-hydroxy benzaldehyde VI with p-aminobenzoic acid gave the corresponding Schiff base VII. Reaction of VII with thioglycollic acid and chloroacetylchloride has been also studied.

Keywords: Heterocylic compounds, biological activity, thioglycollic acid, chloroacetylchloride


Evelin Boshra Moawad. Synthesis of Some New Heterocyclic Compounds with Expected Potential Biological Activity. Med J Islamic World Acad Sci. 1989; 2(4): 237-240

Corresponding Author: Evelin Boshra Moawad, Egypt


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