Pharmacological Effects of 3-Methoxy-Phenacyl-Nicotinium Bromide and Comparison with The Effects of Aspirin on Total Serum Cholesterol in Male Rabbits

Most of the cardiovascular diseases and complications are related with different types of hyperlipidemic conditions. During the course of present research, an attempt has been made to observe the effect of 3-Methoxy-phenacyl-nicotinium bromide as anti-cholesterolemic agent and comparison with the effect of Aspirin. These studies show that 3-Methoxy-phenacyl-nicotinium bromide and Aspirin significantly lowers total serum cholesterol in induced hypercholesterolemic rabbits as compared to untreated (Pathological group). The findings confirm our previous studies where the effects of 2-Methoxy-phenacyl-nicotinium bromide on total lipid, phospholipid, triglyceride, total serum cholesterol and transaminases were investigated on male rabbits (1-3).