Neutrophil, Monocyte and Lymphocyte Chemotaxis in Reiter's Syndrome compared with Rheumatoid Arthritis and Rheumatic Fever

This study was performed to investigate the place of chemotactic activities in differential diagnosis of inflammatory rheumatic disorders. Chemotactic activities of neutrophils, monocytes and lymphocytes of the patients with Reiter's syndrome (RS) (n: 6), rheumatoid arthritis (RA) (n: 10) and rheumatic fever (RF) (n: 19) were determined in peripheral blood samples by Boyden chamber technique. Neutrophil chemotaxis in RS and RF found significantly elevated when compared with RA (p<0.05). No significant difference was found between RS and RF. Monocyte and lymphocyte chemotaxis showed no significance in all three groups. It is interesting that the results of chemotaxis study were similar in RS and RF which were both considered as reactive arthritis.