Serum Tumor Necrosis Factor Alpha Levels in Plasmodium Vivax MalariaEren Erken, Muhsin Akbaba, Ramazan Günesaçar, Hakan Demirhindi, Tülin HergüvençFrom Departments of Immunology and Public Health, Faculty of Medicine, Çukurova University, Adana, Türkiye.
The increase in Tumor Necrosis Factor alpha (TNF-alpha) in Plasmodium falciparum malaria (PFM) has been shown at many previous studies. We aimed to investigate the TNF-alpha levels of Plasmodium vivax malaria (PVM). The study consisted of 19 Plasmodium vivax (PV) patients and a control group of 18 healthy persons. The serum TNF alpha levels were measured by radio-immunoassay method. The TNF alpha levels of the patients (mean=19.67, ± sd ±5.502 pg/ml) were statistically higher in relation to those of the control group (4.63±0.52 pg/ml; p<0.02). Significant increase in TNF alpha in PFM has been shown. It is established that the increase in TNF in PVM is at a lower extent. It is necessary to investigate with further studies the relationship between the clinical signs at paroxysmal periods of PVM patients and serum TNF levels. Keywords: Tumor necrosis factor alpha, TNF-alpha, plasmodium vivax malaria, PVM
Eren Erken, Muhsin Akbaba, Ramazan Günesaçar, Hakan Demirhindi, Tülin Hergüvenç. Serum Tumor Necrosis Factor Alpha Levels in Plasmodium Vivax Malaria. Med J Islamic World Acad Sci. 1993; 6(4): 259-261
Corresponding Author: Eren Erken, Türkiye |
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