The Role of Hydroxamic Acids in Biochemical ProcessesAhmed E. Fazary1, Mohamed M. Khalil2, Aly Fahmy1, Tantawy A. Tantawy11Egyptian Organization for Biological Products and Vaccines (VACSERA), Agouza, Giza, Egypt. 2Department of Chemistry, Faculty of Science, Cairo University, Beni-Suef Branch, Beni-Suef, Egypt.
Hydroxamic acids, a group of naturally occurring and synthetic weak organic acids of general formula RC(=O)N(R')OH, are widespread in the tissues of plants, in metabolites of bacteria and fungi, including complex compounds. Hydroxamic acids and their derivatives fulfill a variety of important roles in biology and medicine; here we provide a comprehensive brief review of the most basic medicinal chemistry and pharmacology of hydroxamate molecules. Keywords: Hydroxamic acids, biological activities, biochemical processes.
Ahmed E. Fazary, Mohamed M. Khalil, Aly Fahmy, Tantawy A. Tantawy. The Role of Hydroxamic Acids in Biochemical Processes. Med J Islamic World Acad Sci. 2001; 14(3): 109-116
Corresponding Author: Ahmed E. Fazary, Egypt |
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