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Med J Islamic World Acad Sci. 1992; 5(2): 81-85
A New Synthesis of 5-Hydroxy-2-Isoxazolines and Their Conversion into Isoxazoles Mohamed G. Marei, Reda A. Ghonaim From Department of Chemistry, Faculty of Science, Alexandria University, Ibrahimia P.O. Box 426, Alexandria 21321, Egypt. The reaction of 1,5-diarylpent-1-yne-3, 5-diones or 2,6-diaryl-4H-pyran-4-ones with hydroxylamine in ethanol led to the formation of 5-hydroxyisoxazolines as well as isoxazoles as minor products. The isoxazolines could be converted into the latter isoxazoles on prolonged heating in xylene. The structure of the intermediate 5-hydroxyisoxazolines was established from their I. R., UV. 1H-N.M.R. and mass spectral data. Keywords: 5-hydroxy-2-isoxazolines, isoxazoles, xylene Mohamed G. Marei, Reda A. Ghonaim. A New Synthesis of 5-Hydroxy-2-Isoxazolines and Their Conversion into Isoxazoles. Med J Islamic World Acad Sci. 1992; 5(2): 81-85 Corresponding Author: Mohamed G. Marei, Türkiye	TOOLS Full Text PDF Print Download citation RIS EndNote BibTex Medlars Procite Reference Manager Share with email Share Send email to author Similar articles PubMed Google Scholar