Cardiovascular Evaluation of Ruellia Patula and Ruellia Brittoniana

Cardiovascular profile of Ruellia patula and Ruellia Brittoniana was carried on isolated rabbit heart. Crude extract, butanolic and aqueous layer of both plants were tested on heart rate, force of contraction and coronary flow. Digoxin was used as a controlled drug. All the fractions showed an increase in force of contraction expect n-butanolic fraction of R. brittoniana which exhibited depression in all parameters. Coronary flow and heart rate displayed non significant decrease. Therefore it was concluded that the given Ruellia plants are of cardiotonic nature.