ISSN 2415-1297 (Online)   ISSN 2415-1300 (Print)
Volume : 30 Issue : 1 Year : 2023
Effect of Aprotinin on Joint Stiffness [Med J Islamic World Acad Sci]
Med J Islamic World Acad Sci. 1988; 1(1): 43-45

Effect of Aprotinin on Joint Stiffness

Sahap O. Atik, Atilla Zenciroglu, Süleyman Bilgili
Department of Orthopedic and Traumatic Surgery, Gazi University, Ankara, Turkiye.

Local aprotinin has been used during arthrotomy both expedimentally in the rats and clinically in the meniscectomy procedure.
Adhesion formation has been evaluated both histopathologically and clinically using the measurements of the Joints' range of motion.
In rats, adhesion rate was 66.66% in the control group, and 15.78 % in the aprotinin treated group P 0.05. Clinically, postoperative rehabilitation period was shorter in the aprotinin treated patients.
The results show that aprotinin significantly reduces the amount of adhesion formation but it does not effect collagen synthesis.

Keywords: Aprotinin Formation, Arthrotomy Formation, Adhesion Formation.

Sahap O. Atik, Atilla Zenciroglu, Süleyman Bilgili. Effect of Aprotinin on Joint Stiffness. Med J Islamic World Acad Sci. 1988; 1(1): 43-45

Corresponding Author: Sahap O. Atik, Türkiye

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